diff --git a/src/flake8/checker.py b/src/flake8/checker.py
index 138bb4f..34db7db 100644
--- a/src/flake8/checker.py
+++ b/src/flake8/checker.py
@@ -73,7 +73,6 @@ class Manager(object):
         self.options = style_guide.options
         self.checks = checker_plugins
         self.jobs = self._job_count()
-        self.using_multiprocessing = self.jobs > 1
         self.processes = []
         self.checkers = []
         self.statistics = {
@@ -279,7 +278,6 @@ class Manager(object):
         except OSError as oserr:
             if oserr.errno not in SERIAL_RETRY_ERRNOS:
                 raise
-            self.using_multiprocessing = False
             self.run_serial()
             return
 
@@ -326,16 +324,10 @@ class Manager(object):
         fallback to serial processing.
         """
         try:
-            if self.using_multiprocessing:
+            if self.jobs > 1 and len(self.checkers) > 1:
                 self.run_parallel()
             else:
                 self.run_serial()
-        except OSError as oserr:
-            if oserr.errno not in SERIAL_RETRY_ERRNOS:
-                LOG.exception(oserr)
-                raise
-            LOG.warning("Running in serial after OS exception, %r", oserr)
-            self.run_serial()
         except KeyboardInterrupt:
             LOG.warning("Flake8 was interrupted by the user")
             raise exceptions.EarlyQuit("Early quit while running checks")
diff --git a/tests/unit/test_checker_manager.py b/tests/unit/test_checker_manager.py
index 2b6cb76..50f4084 100644
--- a/tests/unit/test_checker_manager.py
+++ b/tests/unit/test_checker_manager.py
@@ -16,27 +16,33 @@ def style_guide_mock(**kwargs):
     return style_guide
 
 
+def _parallel_checker_manager():
+    """Call Manager.run() and return the number of calls to `run_serial`."""
+    style_guide = style_guide_mock()
+    manager = checker.Manager(style_guide, [], [])
+    # multiple checkers is needed for parallel mode
+    manager.checkers = [mock.Mock(), mock.Mock()]
+    return manager
+
+
 def test_oserrors_cause_serial_fall_back():
     """Verify that OSErrors will cause the Manager to fallback to serial."""
     err = OSError(errno.ENOSPC, 'Ominous message about spaceeeeee')
-    style_guide = style_guide_mock()
     with mock.patch('_multiprocessing.SemLock', side_effect=err):
-        manager = checker.Manager(style_guide, [], [])
+        manager = _parallel_checker_manager()
         with mock.patch.object(manager, 'run_serial') as serial:
             manager.run()
     assert serial.call_count == 1
-    assert manager.using_multiprocessing is False
 
 
 @mock.patch('flake8.utils.is_windows', return_value=False)
 def test_oserrors_are_reraised(is_windows):
     """Verify that unexpected OSErrors will cause the Manager to reraise."""
     err = OSError(errno.EAGAIN, 'Ominous message')
-    style_guide = style_guide_mock()
     with mock.patch('_multiprocessing.SemLock', side_effect=err):
-        with pytest.raises(OSError):
-            manager = checker.Manager(style_guide, [], [])
-            with mock.patch.object(manager, 'run_serial') as serial:
+        manager = _parallel_checker_manager()
+        with mock.patch.object(manager, 'run_serial') as serial:
+            with pytest.raises(OSError):
                 manager.run()
     assert serial.call_count == 0